The ever expanding abundance of information and computing power enables researchers and users to tackle highly interesting issues for the first time, such as applications providing personalized access and interactivity to multimodal information based on user preferences and semantic concepts or human-machine interface systems utilizing information on the affective state of the user. The purpose of this book is to provide insights on how today’s computer engineers can implement AI in real world applications. Overall, the field of artificial intelligence is extremely broad. In essence, AI has found applications, in one way or another, in every aspect of computing and in most aspects of modern life. Consequently, it is not possible to provide a complete review of the field in the framework of a single book, unless if the review is broad rather than deep. In this book we have chosen to present selected current and emerging practical applications of AI, thus allowing for a more detailed presentation of topics. The book is organized in four parts; General Purpose Applications of AI; Intelligent Human-Computer Interaction; Intelligent Applications in Signal Processing and eHealth; and Real world AI applications in Computer Engineering.